DosePredict 1.0

A One Stop Shop for PK-Based Dose Predictions

Malek Okour, BDS, PhD

Enter Input Values

Project Options:

Author Name:

Compound ID:

Display Options:

Log Scale

90% PI

Individual Subject Lines

Safety & Efficacy Lines

Tick on X axis every:

Simulation Options:

# of Subjects:

Length of Sim:

Dosing Input:

Enter a Dose Vector (Comma Delimited):

II:

ADDL:

Hint: In the current software version, - Only regular dosing is possible. - Only PK-based analysis can be performed.

PK Options:

Select the PK Model:

PK Parameters:

CL:

KA:

F (%):

Scaling :

BP Ratio (fraction):

Between Subject Variability:

CL BSV (%) :

VC BSV (%):

KA BSV (%):

F BSV (%):

CL:

KA:

F (%):

Scaling :

BP Ratio (fraction):

Q1:

V2:

Between Subject Variability:

CL BSV (%) :

VC BSV (%):

KA BSV (%):

F BSV (%):

CL:

KA:

F (%):

Scaling :

BP Ratio (fraction):

Q1:

V2:

Q2:

V3:

Between Subject Variability:

CL BSV (%) :

VC BSV (%):

KA BSV (%):

F BSV (%):

CL:

Scaling :

BP Ratio (fraction):

Between Subject Variability:

CL BSV (%) :

VC BSV (%):

CL:

Scaling :

BP Ratio (fraction):

Q1:

V2:

Between Subject Variability:

CL BSV (%) :

VC BSV (%):

CL:

Scaling :

BP Ratio (fraction):

Q1:

V2:

Q2:

V3:

Between Subject Variability:

CL BSV (%) :

VC BSV (%):

Safety Data:

AUC:

Cmax:

Efficacy Data:

Efficacy Conc Limit :

Efficacy Time Limit :

NCA Calculation Time-Limits:

Time to start the NCA calc:

Time to finish the NCA calc:

Helpful Hint: refresh browser to reset values!

DosePredict 1.0

A One Stop Shop for PK-Based Dose Predictions

Malek Okour, BDS, PhD

Toggle Between Tabs for Output

DosePredict 1.0

A One Stop Shop for PK-Based Dose Predictions

Malek Okour, BDS, PhD

Enter comments related to the current analysis in the shinydashboard::box below

DosePredict 1.0

A One Stop Shop for PK-Based Dose Predictions

Malek Okour, BDS, PhD

Download Simulated Dataset Simulated Dataset

Download NCA Dataset NCA Data

Download Conc Efficacy Dataset Conc Efficacy Data

Download Time Efficacy Dataset Time Efficacy Data

DosePredict 1.0

A One Stop Shop for PK-Based Dose Predictions

Malek Okour, BDS, PhD

Contact Admin

Enter Input Values

Project Options:

Display Options:

Simulation Options:

Dosing Input:

Hint: In the current software version, - Only regular dosing is possible. - Only PK-based analysis can be performed.

PK Options:

PK Parameters:

Between Subject Variability:

Between Subject Variability:

Between Subject Variability:

Between Subject Variability:

Between Subject Variability:

Between Subject Variability:

Safety Data:

Efficacy Data:

NCA Calculation Time-Limits:

Helpful Hint: refresh browser to reset values!

DosePredict 1.0

A One Stop Shop for PK-Based Dose Predictions

Malek Okour, BDS, PhD

Toggle Between Tabs for Output

DosePredict 1.0

A One Stop Shop for PK-Based Dose Predictions

Malek Okour, BDS, PhD

Enter comments related to the current analysis in the shinydashboard::box below

DosePredict 1.0

A One Stop Shop for PK-Based Dose Predictions

Malek Okour, BDS, PhD